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High-Fat Diet-Induced Obese Effects of Adipocyte-Specific CXCR2 Conditional Knockout in the Peritoneal Tumor Microenvironment of Ovarian Cancer

SIMPLE SUMMARY: Obesity contributes to one-fifth of cancer deaths. Ovarian cancer (OC) progression is frequently asymptomatic, making its early detection difficult and its chance of survival low. OC expresses highly tumorigenic chemokines, CXCL1/8, of which the specific receptor CXCR2 is increased i...

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Detalles Bibliográficos
Autores principales: Choe, Deokyeong, Lee, Eun-Sook, Beeghly-Fadiel, Alicia, Wilson, Andrew J., Whalen, Margaret M., Adunyah, Samuel E., Son, Deok-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508092/
https://www.ncbi.nlm.nih.gov/pubmed/34638514
http://dx.doi.org/10.3390/cancers13195033