Metastatic Prostate Cancer Cells Secrete Methylglyoxal-Derived MG-H1 to Reprogram Human Osteoblasts into a Dedifferentiated, Malignant-like Phenotype: A Possible Novel Player in Prostate Cancer Bone Metastases

Bone metastases from prostate cancer (PCa) result from a complex cross-talk between PCa cells and osteoblasts (OB). Thus, targeting this interplay has become an attractive strategy to interfere with PCa bone dissemination. The agents currently used in clinical trials have proved ineffective, boostin...

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Detalles Bibliográficos
Autores principales: Antognelli, Cinzia, Marinucci, Lorella, Frosini, Roberta, Macchioni, Lara, Talesa, Vincenzo Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508123/
https://www.ncbi.nlm.nih.gov/pubmed/34638532
http://dx.doi.org/10.3390/ijms221910191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508123/
https://www.ncbi.nlm.nih.gov/pubmed/34638532
http://dx.doi.org/10.3390/ijms221910191

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