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Transcriptomic Analysis in Multiple Myeloma and Primary Plasma Cell Leukemia with t(11;14) Reveals Different Expression Patterns with Biological Implications in Venetoclax Sensitivity

SIMPLE SUMMARY: The growing interest in BCL2 inhibitors for the treatment of multiple myeloma (MM) has led to the need for biomarkers that are able to predict patient’s sensitivity to the drug. The presence of the chromosomal translocation t(11;14) in MM is mainly associated with sensitivity to vene...

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Detalles Bibliográficos
Autores principales: Todoerti, Katia, Taiana, Elisa, Puccio, Noemi, Favasuli, Vanessa, Lionetti, Marta, Silvestris, Ilaria, Gentile, Massimo, Musto, Pellegrino, Morabito, Fortunato, Gianelli, Umberto, Bolli, Niccolò, Baldini, Luca, Neri, Antonino, Ronchetti, Domenica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508148/
https://www.ncbi.nlm.nih.gov/pubmed/34638381
http://dx.doi.org/10.3390/cancers13194898