The Bul1/2 Alpha-Arrestins Promote Ubiquitylation and Endocytosis of the Can1 Permease upon Cycloheximide-Induced TORC1-Hyperactivation

Selective endocytosis followed by degradation is a major mechanism for downregulating plasma membrane transporters in response to specific environmental cues. In Saccharomyces cerevisiae, this endocytosis is promoted by ubiquitylation catalyzed by the Rsp5 ubiquitin-ligase, targeted to transporters...

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Detalles Bibliográficos
Autores principales: Megarioti, Amalia H., Primo, Cecilia, Kapetanakis, George C., Athanasopoulos, Alexandros, Sophianopoulou, Vicky, André, Bruno, Gournas, Christos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508209/
https://www.ncbi.nlm.nih.gov/pubmed/34638549
http://dx.doi.org/10.3390/ijms221910208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508209/
https://www.ncbi.nlm.nih.gov/pubmed/34638549
http://dx.doi.org/10.3390/ijms221910208

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