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Highlights on the Role of KRAS Mutations in Reshaping the Microenvironment of Pancreatic Adenocarcinoma

The most frequent mutated oncogene family in the history of human cancer is the RAS gene family, including NRAS, HRAS, and, most importantly, KRAS. A hallmark of pancreatic cancer, recalcitrant cancer with a very low survival rate, is the prevalence of oncogenic mutations in the KRAS gene. Due to th...

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Detalles Bibliográficos
Autores principales: Hafezi, Shirin, Saber-Ayad, Maha, Abdel-Rahman, Wael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508406/
https://www.ncbi.nlm.nih.gov/pubmed/34638560
http://dx.doi.org/10.3390/ijms221910219