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Activation of the NLRP3 Inflammasome Increases the IL-1β Level and Decreases GLUT4 Translocation in Skeletal Muscle during Insulin Resistance

Low-grade chronic inflammation plays a pivotal role in the pathogenesis of insulin resistance (IR), and skeletal muscle has a central role in this condition. NLRP3 inflammasome activation pathways promote low-grade chronic inflammation in several tissues. However, a direct link between IR and NLRP3...

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Detalles Bibliográficos
Autores principales: Américo-Da-Silva, Luan, Aguilera, Javiera, Quinteros-Waltemath, Oscar, Sánchez-Aguilera, Pablo, Russell, Javier, Cadagan, Cynthia, Meneses-Valdés, Roberto, Sánchez, Gina, Estrada, Manuel, Jorquera, Gonzalo, Barrientos, Genaro, Llanos, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508423/
https://www.ncbi.nlm.nih.gov/pubmed/34638553
http://dx.doi.org/10.3390/ijms221910212