Regulation of the Expression, Oligomerisation and Signaling of the Inhibitory Receptor CLEC12A by Cysteine Residues in the Stalk Region

CLEC12A is a myeloid inhibitory receptor that negatively regulates inflammation in mouse models of autoimmune and autoinflammatory arthritis. Reduced CLEC12A expression enhances myeloid cell activation and inflammation in CLEC12A knock-out mice with collagen antibody-induced or gout-like arthritis....

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Detalles Bibliográficos
Autores principales: Vitry, Julien, Paré, Guillaume, Murru, Andréa, Charest-Morin, Xavier, Maaroufi, Halim, McLeish, Kenneth R., Naccache, Paul H., Fernandes, Maria J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508511/
https://www.ncbi.nlm.nih.gov/pubmed/34638548
http://dx.doi.org/10.3390/ijms221910207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508511/
https://www.ncbi.nlm.nih.gov/pubmed/34638548
http://dx.doi.org/10.3390/ijms221910207

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