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Regulation of the Expression, Oligomerisation and Signaling of the Inhibitory Receptor CLEC12A by Cysteine Residues in the Stalk Region
CLEC12A is a myeloid inhibitory receptor that negatively regulates inflammation in mouse models of autoimmune and autoinflammatory arthritis. Reduced CLEC12A expression enhances myeloid cell activation and inflammation in CLEC12A knock-out mice with collagen antibody-induced or gout-like arthritis....
Autores principales: | Vitry, Julien, Paré, Guillaume, Murru, Andréa, Charest-Morin, Xavier, Maaroufi, Halim, McLeish, Kenneth R., Naccache, Paul H., Fernandes, Maria J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508511/ https://www.ncbi.nlm.nih.gov/pubmed/34638548 http://dx.doi.org/10.3390/ijms221910207 |
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