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MAPK15 Controls Hedgehog Signaling in Medulloblastoma Cells by Regulating Primary Ciliogenesis
SIMPLE SUMMARY: In eukaryotes, MAPK15 controls the assembly of primary cilia, which are microtubule-based cell surface organelles necessary for sensing and processing developmental signals as well as for transducing tumorigenic Hedgehog signaling in medulloblastomas and basal cell carcinomas. The ai...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508543/ https://www.ncbi.nlm.nih.gov/pubmed/34638386 http://dx.doi.org/10.3390/cancers13194903 |