HER3 PET Imaging: (68)Ga-Labeled Affibody Molecules Provide Superior HER3 Contrast to (89)Zr-Labeled Antibody and Antibody-Fragment-Based Tracers

SIMPLE SUMMARY: HER3 is a known driver for oncogenesis and therapy resistance in solid cancers. PET imaging could be a useful tool to non-invasively detect and monitor HER3 expression and aid in the selection of patients for HER3-targeted therapy. PET tracers based on therapeutic antibodies have thu...

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Detalles Bibliográficos
Autores principales: Rinne, Sara S., Leitao, Charles Dahlsson, Abouzayed, Ayman, Vorobyeva, Anzhelika, Tolmachev, Vladimir, Ståhl, Stefan, Löfblom, John, Orlova, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508546/
https://www.ncbi.nlm.nih.gov/pubmed/34638277
http://dx.doi.org/10.3390/cancers13194791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508546/
https://www.ncbi.nlm.nih.gov/pubmed/34638277
http://dx.doi.org/10.3390/cancers13194791

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