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Cis-Acting Factors Causing Secondary Epimutations: Impact on the Risk for Cancer and Other Diseases

SIMPLE SUMMARY: Epigenetic mechanisms contribute to the regulation of gene expression. However, when they fail, they result in diseases such as cancer. Among these effects is aberrant DNA methylation caused by inherited mutations in cis of the affected gene, referred to as constitutional secondary e...

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Detalles Bibliográficos
Autores principales: Ruiz de la Cruz, Miguel, de la Cruz Montoya, Aldo Hugo, Rojas Jiménez, Ernesto Arturo, Martínez Gregorio, Héctor, Díaz Velásquez, Clara Estela, Paredes de la Vega, Jimena, de la Cruz Hernández-Hernández, Fidel, Vaca Paniagua, Felipe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508567/
https://www.ncbi.nlm.nih.gov/pubmed/34638292
http://dx.doi.org/10.3390/cancers13194807