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Cis-Acting Factors Causing Secondary Epimutations: Impact on the Risk for Cancer and Other Diseases
SIMPLE SUMMARY: Epigenetic mechanisms contribute to the regulation of gene expression. However, when they fail, they result in diseases such as cancer. Among these effects is aberrant DNA methylation caused by inherited mutations in cis of the affected gene, referred to as constitutional secondary e...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508567/ https://www.ncbi.nlm.nih.gov/pubmed/34638292 http://dx.doi.org/10.3390/cancers13194807 |