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Emerging Roles of Astrocyte Kir4.1 Channels in the Pathogenesis and Treatment of Brain Diseases

Inwardly rectifying Kir4.1 channels in astrocytes mediate spatial potassium (K(+)) buffering, a clearance mechanism for excessive extracellular K(+), in tripartite synapses. In addition to K(+) homeostasis, astrocytic Kir4.1 channels also play an essential role in regulating extracellular glutamate...

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Detalles Bibliográficos
Autores principales: Ohno, Yukihiro, Kunisawa, Naofumi, Shimizu, Saki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508600/
https://www.ncbi.nlm.nih.gov/pubmed/34638578
http://dx.doi.org/10.3390/ijms221910236