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Emerging Roles of Astrocyte Kir4.1 Channels in the Pathogenesis and Treatment of Brain Diseases
Inwardly rectifying Kir4.1 channels in astrocytes mediate spatial potassium (K(+)) buffering, a clearance mechanism for excessive extracellular K(+), in tripartite synapses. In addition to K(+) homeostasis, astrocytic Kir4.1 channels also play an essential role in regulating extracellular glutamate...
Autores principales: | Ohno, Yukihiro, Kunisawa, Naofumi, Shimizu, Saki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508600/ https://www.ncbi.nlm.nih.gov/pubmed/34638578 http://dx.doi.org/10.3390/ijms221910236 |
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