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Regulation of O-Linked N-Acetyl Glucosamine Transferase (OGT) through E6 Stimulation of the Ubiquitin Ligase Activity of E6AP

Glycosyltransferase OGT catalyzes the conjugation of O-linked β-D-N-acetylglucosamine (O-GlcNAc) to Ser and Thr residues of the cellular proteins and regulates many key processes in the cell. Here, we report the identification of OGT as a ubiquitination target of HECT-type E3 ubiquitin (UB) ligase E...

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Detalles Bibliográficos
Autores principales: Peng, Kangli, Liu, Ruochuan, Jia, Caiwei, Wang, Yiyang, Jeong, Geon H., Zhou, Li, Hu, Ronggui, Kiyokawa, Hiroaki, Yin, Jun, Zhao, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508608/
https://www.ncbi.nlm.nih.gov/pubmed/34638625
http://dx.doi.org/10.3390/ijms221910286