Nitro-Deficient Niclosamide Confers Reduced Genotoxicity and Retains Mitochondrial Uncoupling Activity for Cancer Therapy

Niclosamide is an oral anthelmintic drug, approved for use against tapeworm infections. Recent studies suggest however that niclosamide may have broader clinical applications in cancers, spurring increased interest in the functions and mechanisms of niclosamide. Previously, we reported that niclosam...

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Detalles Bibliográficos
Autores principales: Ngai, Tsz Wai, Elfar, Gamal Ahmed, Yeo, Pearlyn, Phua, Nicholas, Hor, Jin Hui, Chen, Shuwen, Ho, Ying Swan, Cheok, Chit Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508655/
https://www.ncbi.nlm.nih.gov/pubmed/34638761
http://dx.doi.org/10.3390/ijms221910420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508655/
https://www.ncbi.nlm.nih.gov/pubmed/34638761
http://dx.doi.org/10.3390/ijms221910420

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