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Nitro-Deficient Niclosamide Confers Reduced Genotoxicity and Retains Mitochondrial Uncoupling Activity for Cancer Therapy
Niclosamide is an oral anthelmintic drug, approved for use against tapeworm infections. Recent studies suggest however that niclosamide may have broader clinical applications in cancers, spurring increased interest in the functions and mechanisms of niclosamide. Previously, we reported that niclosam...
Autores principales: | Ngai, Tsz Wai, Elfar, Gamal Ahmed, Yeo, Pearlyn, Phua, Nicholas, Hor, Jin Hui, Chen, Shuwen, Ho, Ying Swan, Cheok, Chit Fang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508655/ https://www.ncbi.nlm.nih.gov/pubmed/34638761 http://dx.doi.org/10.3390/ijms221910420 |
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