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In Silico Modeling of the Influence of Environment on Amyloid Folding Using FOD-M Model

The role of the environment in amyloid formation based on the fuzzy oil drop model (FOD) is discussed here. This model assumes that the hydrophobicity distribution within a globular protein is consistent with a 3D Gaussian (3DG) distribution. Such a distribution is interpreted as the idealized effec...

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Detalles Bibliográficos
Autores principales: Roterman, Irena, Stapor, Katarzyna, Fabian, Piotr, Konieczny, Leszek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508659/
https://www.ncbi.nlm.nih.gov/pubmed/34638925
http://dx.doi.org/10.3390/ijms221910587