Novel P2X7 Antagonist Ameliorates the Early Phase of ALS Disease and Decreases Inflammation and Autophagy in SOD1-G93A Mouse Model

Amyotrophic lateral sclerosis (ALS) is a disease with a resilient neuroinflammatory component caused by activated microglia and infiltrated immune cells. How to successfully balance neuroprotective versus neurotoxic actions through the use of anti-inflammatory agents is still under debate. There has...

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Detalles Bibliográficos
Autores principales: Apolloni, Savina, Fabbrizio, Paola, Amadio, Susanna, Napoli, Giulia, Freschi, Mattia, Sironi, Francesca, Pevarello, Paolo, Tarroni, Paola, Liberati, Chiara, Bendotti, Caterina, Volonté, Cinzia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508678/
https://www.ncbi.nlm.nih.gov/pubmed/34638992
http://dx.doi.org/10.3390/ijms221910649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508678/
https://www.ncbi.nlm.nih.gov/pubmed/34638992
http://dx.doi.org/10.3390/ijms221910649

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