The Ephb2 Receptor Uses Homotypic, Head-to-Tail Interactions within Its Ectodomain as an Autoinhibitory Control Mechanism

The Eph receptor tyrosine kinases and their ephrin ligands direct axon pathfinding and neuronal cell migration, as well as mediate many other cell–cell communication events. Their dysfunctional signaling has been shown to lead to various diseases, including cancer. The Ephs and ephrins both localize...

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Detalles Bibliográficos
Autores principales: Xu, Yan, Robev, Dorothea, Saha, Nayanendu, Wang, Bingcheng, Dalva, Matthew B., Xu, Kai, Himanen, Juha P., Nikolov, Dimitar B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508685/
https://www.ncbi.nlm.nih.gov/pubmed/34638814
http://dx.doi.org/10.3390/ijms221910473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508685/
https://www.ncbi.nlm.nih.gov/pubmed/34638814
http://dx.doi.org/10.3390/ijms221910473

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