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Cyclodextrins Allow the Combination of Incompatible Vancomycin and Ceftazidime into an Ophthalmic Formulation for the Treatment of Bacterial Keratitis

Ceftazidime (CZ) and vancomycin (VA) are two antibiotics used to treat bacterial keratitis. Due to their physical incompatibility (formation of a precipitate), it is not currently possible to associate both molecules in a single container for ophthalmic administration. We firstly characterized the i...

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Detalles Bibliográficos
Autores principales: Bouattour, Yassine, Neflot-Bissuel, Florent, Traïkia, Mounir, Biesse-Martin, Anne-Sophie, Frederic, Robin, Yessaad, Mouloud, Jouannet, Mireille, Wasiak, Mathieu, Chennell, Philip, Sautou, Valerie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508691/
https://www.ncbi.nlm.nih.gov/pubmed/34638878
http://dx.doi.org/10.3390/ijms221910538