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Disulfiram Sensitizes a Therapeutic-Resistant Glioblastoma to the TGF-β Receptor Inhibitor

Despite neurosurgery following radiation and chemotherapy, residual glioblastoma (GBM) cells develop therapeutic resistance (TR) leading to recurrence. The GBM heterogeneity confers TR. Therefore, an effective strategy must target cancer stem cells (CSCs) and other malignant cancer cells. TGF-β and...

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Detalles Bibliográficos
Autores principales: Liu, Chan-Chuan, Wu, Cheng-Lin, Lin, Meng-Xuan, Sze, Chun-I, Gean, Po-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508702/
https://www.ncbi.nlm.nih.gov/pubmed/34638842
http://dx.doi.org/10.3390/ijms221910496