Three-Dimensional Liver Culture Systems to Maintain Primary Hepatic Properties for Toxicological Analysis In Vitro

Drug-induced liver injury (DILI) is the major reason for failures in drug development and withdrawal of approved drugs from the market. Two-dimensional cultures of hepatocytes often fail to reliably predict DILI: hepatoma cell lines such as HepG2 do not reflect important primary-like hepatic propert...

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Detalles Bibliográficos
Autor principal: Kammerer, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508724/
https://www.ncbi.nlm.nih.gov/pubmed/34638555
http://dx.doi.org/10.3390/ijms221910214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508724/
https://www.ncbi.nlm.nih.gov/pubmed/34638555
http://dx.doi.org/10.3390/ijms221910214

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