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Diosgenin Prevents Microglial Activation and Protects Dopaminergic Neurons from Lipopolysaccharide-Induced Neural Damage In Vitro and In Vivo

Background: The prevention of age-related neurodegenerative disorders is an important issue in an aging society. Microglia-mediated neuroinflammation resulting in dopaminergic neuron loss may lead to the pathogenesis of Parkinson’s disease (PD). Lipopolysaccharide (LPS), an endotoxin, induces neuroi...

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Detalles Bibliográficos
Autores principales: Lee, Shou-Lun, Tu, Ssu-Chieh, Hsu, Ming-Yen, Chin, Ting-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508726/
https://www.ncbi.nlm.nih.gov/pubmed/34638697
http://dx.doi.org/10.3390/ijms221910361