BRET Analysis of GPCR Dimers in Neurons and Non-Neuronal Cells: Evidence for Inactive, Agonist, and Constitutive Conformations

G-protein-coupled receptors (GPCRs) are dimeric proteins, but the functional consequences of the process are still debated. Active GPCR conformations are promoted either by agonists or constitutive activity. Inverse agonists decrease constitutive activity by promoting inactive conformations. The his...

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Detalles Bibliográficos
Autores principales: El Khamlichi, Chayma, Cobret, Laetitia, Arrang, Jean-Michel, Morisset-Lopez, Séverine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508734/
https://www.ncbi.nlm.nih.gov/pubmed/34638980
http://dx.doi.org/10.3390/ijms221910638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508734/
https://www.ncbi.nlm.nih.gov/pubmed/34638980
http://dx.doi.org/10.3390/ijms221910638

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