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Kansuinine A Ameliorates Atherosclerosis and Human Aortic Endothelial Cell Apoptosis by Inhibiting Reactive Oxygen Species Production and Suppressing IKKβ/IκBα/NF-κB Signaling

Reactive oxygen species (ROS)-induced vascular endothelial cell apoptosis is strongly associated with atherosclerosis progression. Herein, we aimed to examine whether Kansuinine A (KA), extracted from Euphorbia kansui L., prevents atherosclerosis development in a mouse model and inhibits cell apopto...

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Detalles Bibliográficos
Autores principales: Chen, Chen-Sheng, Pan, Bo-Yi, Tsai, Ping-Hsuan, Chen, Fang-Yu, Yang, Wen-Chin, Shen, Ming-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508741/
https://www.ncbi.nlm.nih.gov/pubmed/34638650
http://dx.doi.org/10.3390/ijms221910309