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A Systematic Review and Meta-Analysis on the Significance of TIGIT in Solid Cancers: Dual TIGIT/PD-1 Blockade to Overcome Immune-Resistance in Solid Cancers

Preclinical studies have indicated that T-cell immunoglobulin and ITIM domain (TIGIT) can substantially attenuate anti-tumoral immune responses. Although multiple clinical studies have evaluated the significance of TIGIT in patients with solid cancers, their results remain inconclusive. Thus, we con...

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Detalles Bibliográficos
Autores principales: Hosseinkhani, Negar, Shadbad, Mahdi Abdoli, Asghari Jafarabadi, Mohammad, Karim Ahangar, Noora, Asadzadeh, Zahra, Mohammadi, Seyede Momeneh, Lotfinejad, Parisa, Alizadeh, Nazila, Brunetti, Oronzo, Fasano, Rossella, Silvestris, Nicola, Baradaran, Behzad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508743/
https://www.ncbi.nlm.nih.gov/pubmed/34638729
http://dx.doi.org/10.3390/ijms221910389