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Leptin Reduces Plin5 m(6)A Methylation through FTO to Regulate Lipolysis in Piglets

Perilipin5 (Plin5) is a scaffold protein that plays an important role in lipid droplets (LD) formation, but the regulatory effect of leptin on it is unclear. Our study aimed to explore the underlying mechanisms by which leptin reduces the N(6)-methyladenosine (m(6)A) methylation of Plin5 through fat...

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Detalles Bibliográficos
Autores principales: Wei, Dongqin, Sun, Qian, Li, Yizhou, Li, Chaowei, Li, Xinjian, Sun, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508756/
https://www.ncbi.nlm.nih.gov/pubmed/34638947
http://dx.doi.org/10.3390/ijms221910610