Halting Tumor Progression via Novel Non-Hydroxamate Triazole-Based Mannich Bases MMP-2/9 Inhibitors; Design, Microwave-Assisted Synthesis, and Biological Evaluation

Matrix metalloproteinases (MMPs) are key signaling modulators in the tumor microenvironment. Among MMPs, MMP-2 and MMP-9 are receiving renewed interest as validated druggable targets for halting different tumor progression events. Over the last decades, a diverse range of MMP-2/9 inhibitors has been...

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Detalles Bibliográficos
Autores principales: Albelwi, Fawzia Faleh, Teleb, Mohamed, Abu-Serie, Marwa M., Moaty, Mohamed Nabil Abd Al, Alsubaie, Mai S., Zakaria, Mohamed A., El Kilany, Yeldez, Aouad, Mohamed Reda, Hagar, Mohamed, Rezki, Nadjet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508768/
https://www.ncbi.nlm.nih.gov/pubmed/34638665
http://dx.doi.org/10.3390/ijms221910324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508768/
https://www.ncbi.nlm.nih.gov/pubmed/34638665
http://dx.doi.org/10.3390/ijms221910324

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