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Role of L-Type Voltage-Gated Calcium Channels in Epileptiform Activity of Neurons

Epileptic discharges manifest in individual neurons as abnormal membrane potential fluctuations called paroxysmal depolarization shift (PDS). PDSs can combine into clusters that are accompanied by synchronous oscillations of the intracellular Ca(2+) concentration ([Ca(2+)](i)) in neurons. Here, we i...

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Detalles Bibliográficos
Autores principales: Laryushkin, Denis P., Maiorov, Sergei A., Zinchenko, Valery P., Gaidin, Sergei G., Kosenkov, Artem M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508770/
https://www.ncbi.nlm.nih.gov/pubmed/34638683
http://dx.doi.org/10.3390/ijms221910342