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Quinacrine Ameliorates Cisplatin-Induced Renal Toxicity via Modulation of Sirtuin-1 Pathway

Renal toxicity is a serious side effect that hinders the use of cisplatin, a commonly used and effective chemotherapeutic agent. Meanwhile, quinacrine is an FDA approved drug that has been stated for its anti-inflammatory effect. Thus, we investigated the ameliorative effect of quinacrine against ci...

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Detalles Bibliográficos
Autores principales: Abo El-Magd, Nada F., Ebrahim, Hasnaa Ali, El-Sherbiny, Mohamed, Eisa, Nada H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508772/
https://www.ncbi.nlm.nih.gov/pubmed/34639002
http://dx.doi.org/10.3390/ijms221910660