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A Chimeric IL-15/IL-15Rα Molecule Expressed on NFκB-Activated Dendritic Cells Supports Their Capability to Activate Natural Killer Cells †

Natural killer (NK) cells, members of the innate immune system, play an important role in the rejection of HLA class I negative tumor cells. Hence, a therapeutic vaccine, which can activate NK cells in addition to cells of the adaptive immune system might induce a more comprehensive cellular respons...

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Detalles Bibliográficos
Autores principales: Bosch, Naomi C., Martin, Lena-Marie, Voskens, Caroline J., Berking, Carola, Seliger, Barbara, Schuler, Gerold, Schaft, Niels, Dörrie, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508776/
https://www.ncbi.nlm.nih.gov/pubmed/34638566
http://dx.doi.org/10.3390/ijms221910227