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Clinical Trials of Broadly Neutralizing Monoclonal Antibodies for Human Immunodeficiency Virus Prevention: A Review

Passive immunization with broadly neutralizing antibodies (bnAbs) is a promising approach to reduce the 1.7 million annual human immunodeficiency virus (HIV) infections globally. Early studies on bnAbs showed safety in humans, but short elimination half-lives and low potency and breadth. Since 2010,...

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Detalles Bibliográficos
Autores principales: Mahomed, Sharana, Garrett, Nigel, Baxter, Cheryl, Abdool Karim, Quarraisha, Abdool Karim, Salim S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508778/
https://www.ncbi.nlm.nih.gov/pubmed/32604408
http://dx.doi.org/10.1093/infdis/jiaa377