Synthesis and In Silico Docking of New Pyrazolo[4,3-e]pyrido[1,2-a]pyrimidine-based Cytotoxic Agents

To explore a new set of anticancer agents, a novel series of pyrazolo[4,3-e]pyrido[1,2-a]pyrimidine derivativeshave been designed and synthesized viacyclocondensation reactions of pyrazolo-enaminone with a series of arylidenemalononitriles; compound 5 was obtained from 5-amino-4-cyanopyrazole. The s...

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Detalles Bibliográficos
Autores principales: Horchani, Mabrouk, Heise, Niels V., Hoenke, Sophie, Csuk, René, Harrath, Abdel Halim, Ben Jannet, Hichem, Romdhane, Anis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508785/
https://www.ncbi.nlm.nih.gov/pubmed/34638600
http://dx.doi.org/10.3390/ijms221910258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508785/
https://www.ncbi.nlm.nih.gov/pubmed/34638600
http://dx.doi.org/10.3390/ijms221910258

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