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Discovery and Validation of Lmj_04_BRCT Domain, a Novel Therapeutic Target: Identification of Candidate Drugs for Leishmaniasis

Since many of the currently available antileishmanial treatments exhibit toxicity, low effectiveness, and resistance, search and validation of new therapeutic targets allowing the development of innovative drugs have become a worldwide priority. This work presents a structure-based drug discovery st...

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Detalles Bibliográficos
Autores principales: Peña-Guerrero, José, Fernández-Rubio, Celia, Burguete-Mikeo, Aroia, El-Dirany, Rima, García-Sosa, Alfonso T., Nguewa, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508789/
https://www.ncbi.nlm.nih.gov/pubmed/34638841
http://dx.doi.org/10.3390/ijms221910493