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Discovery and Validation of Lmj_04_BRCT Domain, a Novel Therapeutic Target: Identification of Candidate Drugs for Leishmaniasis
Since many of the currently available antileishmanial treatments exhibit toxicity, low effectiveness, and resistance, search and validation of new therapeutic targets allowing the development of innovative drugs have become a worldwide priority. This work presents a structure-based drug discovery st...
Autores principales: | Peña-Guerrero, José, Fernández-Rubio, Celia, Burguete-Mikeo, Aroia, El-Dirany, Rima, García-Sosa, Alfonso T., Nguewa, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508789/ https://www.ncbi.nlm.nih.gov/pubmed/34638841 http://dx.doi.org/10.3390/ijms221910493 |
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