Metformin Affects Olaparib Sensitivity through Induction of Apoptosis in Epithelial Ovarian Cancer Cell Lines

This study examined the effect of combination treatment with the poly (ADP-ribose) polymerase inhibitor olaparib and metformin on homologous recombination (HR)-proficient epithelial ovarian cancer (EOC). Ovarian cancer cell lines (OV-90 and SKOV-3) were treated with olaparib, metformin, or a combina...

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Detalles Bibliográficos
Autores principales: Gralewska, Patrycja, Gajek, Arkadiusz, Marczak, Agnieszka, Rogalska, Aneta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508816/
https://www.ncbi.nlm.nih.gov/pubmed/34638899
http://dx.doi.org/10.3390/ijms221910557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508816/
https://www.ncbi.nlm.nih.gov/pubmed/34638899
http://dx.doi.org/10.3390/ijms221910557

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