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The FMN “140s Loop” of Cytochrome P450 Reductase Controls Electron Transfer to Cytochrome P450

Cytochrome P450 reductase (CYPOR) provides electrons to all human microsomal cytochrome P450s (cyt P450s). The length and sequence of the “140s” FMN binding loop of CYPOR has been shown to be a key determinant of its redox potential and activity with cyt P450s. Shortening the “140s loop” by deleting...

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Detalles Bibliográficos
Autores principales: Rwere, Freeborn, Im, Sangchoul, Waskell, Lucy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508823/
https://www.ncbi.nlm.nih.gov/pubmed/34638963
http://dx.doi.org/10.3390/ijms221910625