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MS-275 (Entinostat) Promotes Radio-Sensitivity in PAX3-FOXO1 Rhabdomyosarcoma Cells

Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma of childhood. About 25% of RMS expresses fusion oncoproteins such as PAX3/PAX7-FOXO1 (fusion-positive, FP) while fusion-negative (FN)-RMS harbors RAS mutations. Radiotherapy (RT) plays a crucial role in local control but metastatic RMS is...

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Detalles Bibliográficos
Autores principales: Cassandri, Matteo, Pomella, Silvia, Rossetti, Alessandra, Petragnano, Francesco, Milazzo, Luisa, Vulcano, Francesca, Camero, Simona, Codenotti, Silvia, Cicchetti, Francesca, Maggio, Roberto, Festuccia, Claudio, Gravina, Giovanni Luca, Fanzani, Alessandro, Megiorni, Francesca, Catanoso, Marialuigia, Marchese, Cinzia, Tombolini, Vincenzo, Locatelli, Franco, Rota, Rossella, Marampon, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508838/
https://www.ncbi.nlm.nih.gov/pubmed/34639012
http://dx.doi.org/10.3390/ijms221910671