Comparative Analysis of Genome Editors Efficiency on a Model of Mice Zygotes Microinjection

Genome editing is an indispensable tool for functional genomics. The caveat of the genome-editing pipeline is a prevalence of error-prone non-homologous end joining over homologous recombination, while only the latter is suitable to introduce particularly desired genetic variants. To overcome this p...

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Detalles Bibliográficos
Autores principales: Averina, Olga A., Permyakov, Oleg A., Grigorieva, Olga O., Starshin, Alexey S., Mazur, Alexander M., Prokhortchouk, Egor B., Dontsova, Olga A., Sergiev, Petr V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508852/
https://www.ncbi.nlm.nih.gov/pubmed/34638562
http://dx.doi.org/10.3390/ijms221910221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508852/
https://www.ncbi.nlm.nih.gov/pubmed/34638562
http://dx.doi.org/10.3390/ijms221910221

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