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Comparative Analysis of Genome Editors Efficiency on a Model of Mice Zygotes Microinjection
Genome editing is an indispensable tool for functional genomics. The caveat of the genome-editing pipeline is a prevalence of error-prone non-homologous end joining over homologous recombination, while only the latter is suitable to introduce particularly desired genetic variants. To overcome this p...
Autores principales: | Averina, Olga A., Permyakov, Oleg A., Grigorieva, Olga O., Starshin, Alexey S., Mazur, Alexander M., Prokhortchouk, Egor B., Dontsova, Olga A., Sergiev, Petr V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508852/ https://www.ncbi.nlm.nih.gov/pubmed/34638562 http://dx.doi.org/10.3390/ijms221910221 |
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