Reduced Endothelial Leptin Signaling Increases Vascular Adrenergic Reactivity in a Mouse Model of Congenital Generalized Lipodystrophy

The adipokine leptin, which is best-known for its role in the control of metabolic function, is also a master regulator of cardiovascular function. While leptin has been approved for the treatment of metabolic disorders in patients with congenital generalized lipodystrophy (CGL), the effects of chro...

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Detalles Bibliográficos
Autores principales: Bruder-Nascimento, Thiago, Kress, Taylor C., Pearson, Matthew, Chen, Weiqin, Kennard, Simone, Belin de Chantemèle, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508873/
https://www.ncbi.nlm.nih.gov/pubmed/34638939
http://dx.doi.org/10.3390/ijms221910596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508873/
https://www.ncbi.nlm.nih.gov/pubmed/34638939
http://dx.doi.org/10.3390/ijms221910596

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