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Reduced Endothelial Leptin Signaling Increases Vascular Adrenergic Reactivity in a Mouse Model of Congenital Generalized Lipodystrophy
The adipokine leptin, which is best-known for its role in the control of metabolic function, is also a master regulator of cardiovascular function. While leptin has been approved for the treatment of metabolic disorders in patients with congenital generalized lipodystrophy (CGL), the effects of chro...
Autores principales: | Bruder-Nascimento, Thiago, Kress, Taylor C., Pearson, Matthew, Chen, Weiqin, Kennard, Simone, Belin de Chantemèle, Eric J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508873/ https://www.ncbi.nlm.nih.gov/pubmed/34638939 http://dx.doi.org/10.3390/ijms221910596 |
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