Cargando…

Reduced Endothelial Leptin Signaling Increases Vascular Adrenergic Reactivity in a Mouse Model of Congenital Generalized Lipodystrophy

The adipokine leptin, which is best-known for its role in the control of metabolic function, is also a master regulator of cardiovascular function. While leptin has been approved for the treatment of metabolic disorders in patients with congenital generalized lipodystrophy (CGL), the effects of chro...

Descripción completa

Detalles Bibliográficos
Autores principales: Bruder-Nascimento, Thiago, Kress, Taylor C., Pearson, Matthew, Chen, Weiqin, Kennard, Simone, Belin de Chantemèle, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508873/
https://www.ncbi.nlm.nih.gov/pubmed/34638939
http://dx.doi.org/10.3390/ijms221910596

Ejemplares similares