Difluoromethylornithine Induces Apoptosis through Regulation of AP-1 Signaling via JNK Phosphorylation in Epithelial Ovarian Cancer

Difluoromethylornithine (DFMO), an irreversible inhibitor of ornithine decarboxylase (ODC), has promising activity against various cancers and a tolerable safety profile for long-term use as a chemopreventive agent. However, the anti-tumor effects of DFMO in ovarian cancer cells have not been entire...

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Detalles Bibliográficos
Autores principales: Hwang, Woo Yeon, Park, Wook Ha, Suh, Dong Hoon, Kim, Kidong, Kim, Yong Beom, No, Jae Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508876/
https://www.ncbi.nlm.nih.gov/pubmed/34638596
http://dx.doi.org/10.3390/ijms221910255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508876/
https://www.ncbi.nlm.nih.gov/pubmed/34638596
http://dx.doi.org/10.3390/ijms221910255

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