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Difluoromethylornithine Induces Apoptosis through Regulation of AP-1 Signaling via JNK Phosphorylation in Epithelial Ovarian Cancer
Difluoromethylornithine (DFMO), an irreversible inhibitor of ornithine decarboxylase (ODC), has promising activity against various cancers and a tolerable safety profile for long-term use as a chemopreventive agent. However, the anti-tumor effects of DFMO in ovarian cancer cells have not been entire...
Autores principales: | Hwang, Woo Yeon, Park, Wook Ha, Suh, Dong Hoon, Kim, Kidong, Kim, Yong Beom, No, Jae Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508876/ https://www.ncbi.nlm.nih.gov/pubmed/34638596 http://dx.doi.org/10.3390/ijms221910255 |
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