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Bona Fide Tumor Suppressor Genes Hypermethylated in Melanoma: A Narrative Review

Loss-of-function events in tumor suppressor genes (TSGs) contribute to the development and progression of cutaneous malignant melanoma (CMM). Epigenetic alterations are the major mechanisms of TSG inactivation, in particular, silencing by promoter CpG-island hypermethylation. TSGs are valuable tools...

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Detalles Bibliográficos
Autores principales: Güvenç, Canan, Neckebroeck, Fien, Antoranz, Asier, Garmyn, Marjan, van den Oord, Joost, Bosisio, Francesca Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508892/
https://www.ncbi.nlm.nih.gov/pubmed/34639015
http://dx.doi.org/10.3390/ijms221910674