Upregulation of the APOBEC3 Family Is Associated with a Poor Prognosis and Influences Treatment Response to Raf Inhibitors in Low Grade Glioma

Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3 (APOBEC3) has been identified as a group of enzymes that catalyze cytosine deamination in single-stranded (ss) DNA to form uracil, causing somatic mutations in some cancers. We analyzed the APOBEC3 family in 33 TCGA cancer types and t...

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Detalles Bibliográficos
Autores principales: Luo, Cheng, Wang, Songmao, Liao, Weijie, Zhang, Shikuan, Xu, Naihan, Xie, Weidong, Zhang, Yaou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508917/
https://www.ncbi.nlm.nih.gov/pubmed/34638749
http://dx.doi.org/10.3390/ijms221910390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508917/
https://www.ncbi.nlm.nih.gov/pubmed/34638749
http://dx.doi.org/10.3390/ijms221910390

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