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Rab11-FIP1 and Rab11-FIP5 Regulate pIgR/pIgA Transcytosis through TRIM21-Mediated Polyubiquitination

Polymeric immunoglobulin receptor (pIgR)-mediated polymeric immunoglobulin A (pIgA) transcytosis across mucosal epithelial cells plays an essential role in mucosal immunity. The general trafficking process has been well investigated, yet the elaborate regulatory mechanisms remain enigmatic. We ident...

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Detalles Bibliográficos
Autores principales: Fan, Xuxu, Zhou, Dihan, Zhao, Bali, Sha, Huijun, Li, Mengxue, Li, Xian, Yang, Jingyi, Yan, Huimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508952/
https://www.ncbi.nlm.nih.gov/pubmed/34638806
http://dx.doi.org/10.3390/ijms221910466