Ruthenium Half-Sandwich Type Complexes with Bidentate Monosaccharide Ligands Show Antineoplastic Activity in Ovarian Cancer Cell Models through Reactive Oxygen Species Production

Ruthenium complexes are developed as substitutes for platinum complexes to be used in the chemotherapy of hematological and gynecological malignancies, such as ovarian cancer. We synthesized and screened 14 ruthenium half-sandwich complexes with bidentate monosaccharide ligands in ovarian cancer cel...

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Detalles Bibliográficos
Autores principales: Kacsir, István, Sipos, Adrienn, Ujlaki, Gyula, Buglyó, Péter, Somsák, László, Bai, Péter, Bokor, Éva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508960/
https://www.ncbi.nlm.nih.gov/pubmed/34638791
http://dx.doi.org/10.3390/ijms221910454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508960/
https://www.ncbi.nlm.nih.gov/pubmed/34638791
http://dx.doi.org/10.3390/ijms221910454

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