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Ruthenium Half-Sandwich Type Complexes with Bidentate Monosaccharide Ligands Show Antineoplastic Activity in Ovarian Cancer Cell Models through Reactive Oxygen Species Production
Ruthenium complexes are developed as substitutes for platinum complexes to be used in the chemotherapy of hematological and gynecological malignancies, such as ovarian cancer. We synthesized and screened 14 ruthenium half-sandwich complexes with bidentate monosaccharide ligands in ovarian cancer cel...
Autores principales: | Kacsir, István, Sipos, Adrienn, Ujlaki, Gyula, Buglyó, Péter, Somsák, László, Bai, Péter, Bokor, Éva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8508960/ https://www.ncbi.nlm.nih.gov/pubmed/34638791 http://dx.doi.org/10.3390/ijms221910454 |
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